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Product details

Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL

Catalog number BNC881100-500

Price for BNC881100-500

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Size / count 1x 500 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRTL/KRTH is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881100-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT76, KRT77
Gene ID
374454 (KRT77) & 51350 (KRT76)
Host
Mouse
Species Reactivity
Human, Rat
Reactivity
Cytokeratin, pan
Immunogen
Recombinant human KRT77 and KRT76 protein
Target Antigen
Cytokeratin, pan
Clonality
Monoclonal
Clone
KRTL/1077 KRTH/1076
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
Skin, Adeno- or Squamous carcinomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL is BNC881100-500.

What sizes are available for Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL?

Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL in stock?

Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL?

Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin, pan (KRTL/1077 + KRTH/1076), CF488A conjugate, 0.1mg/mL used for?

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies h

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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