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Product details

EGFR (GFR1195), CF647 conjugate, 0.1mg/mL

Catalog number BNC471195-500

Price for BNC471195-500

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Size / count 1x 500 µL

About this product

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, β cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471195-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EGFR
Gene ID
1956
NCBI Gene ID
488293
UniProt
P00533
Swiss Prot
P00533
Host
Mouse
Species Reactivity
Human
Reactivity
EGFR
Immunogen
Recombinant human EGFR protein
Target Antigen
EGFR
Clonality
Monoclonal
Clone
GFR1195
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Signal transduction
Positive Control
A431 cells. Placenta, Breast, Colon or Bladder cancer
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~170 kDa (wild type) and ~145 kDa (vIII variant)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for EGFR (GFR1195), CF647 conjugate, 0.1mg/mL?

The catalog number for EGFR (GFR1195), CF647 conjugate, 0.1mg/mL is BNC471195-500.

What sizes are available for EGFR (GFR1195), CF647 conjugate, 0.1mg/mL?

EGFR (GFR1195), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is EGFR (GFR1195), CF647 conjugate, 0.1mg/mL in stock?

EGFR (GFR1195), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR (GFR1195), CF647 conjugate, 0.1mg/mL?

EGFR (GFR1195), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFR (GFR1195), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for EGFR (GFR1195), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFR (GFR1195), CF647 conjugate, 0.1mg/mL?

The safety data sheet for EGFR (GFR1195), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b3061270361e10a698/msds/bnc471195-500.pdf.

What is EGFR (GFR1195), CF647 conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, β c

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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