Product details

EGFR (GFR450), 0.2mg/mL

Catalog number BNUB0450-500

Price for BNUB0450-500

Size / count 1x 500 µL

About this product

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, β cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB0450-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EGFR
Gene ID: 1956
NCBI Gene ID: 488293
UniProt: P00533
Swiss Prot: P00533
Host: Mouse
Species Reactivity: Human
Reactivity: EGFR
Immunogen: Recombinant extracellular domain of human EGFR protein
Target Antigen: EGFR
Clonality: Monoclonal
Clone: GFR450
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified)
Field of Research: Cancer, Signal transduction
Positive Control: A431 cells, Breast or Bladder cancer
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: ~170 kDa (wild type) and ~145 kDa (vIII variant)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for EGFR (GFR450), 0.2mg/mL?

The catalog number for EGFR (GFR450), 0.2mg/mL is BNUB0450-500.

What sizes are available for EGFR (GFR450), 0.2mg/mL?

EGFR (GFR450), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is EGFR (GFR450), 0.2mg/mL in stock?

EGFR (GFR450), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR (GFR450), 0.2mg/mL?

EGFR (GFR450), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFR (GFR450), 0.2mg/mL?

Estimated delivery time for EGFR (GFR450), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFR (GFR450), 0.2mg/mL?

The safety data sheet for EGFR (GFR450), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102848/msds/bnub0450-500.pdf.

What is EGFR (GFR450), 0.2mg/mL used for?

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.