Product details

EGFR (GFR450), 1mg/mL

Catalog number BNUM0450-50

Price for BNUM0450-50

Size / count 1x 50 µL

About this product

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, β cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM0450-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EGFR
Gene ID: 1956
NCBI Gene ID: 488293
UniProt: P00533
Swiss Prot: P00533
Host: Mouse
Species Reactivity: Human
Reactivity: EGFR
Immunogen: Recombinant extracellular domain of human EGFR protein
Target Antigen: EGFR
Clonality: Monoclonal
Clone: GFR450
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified)
Field of Research: Cancer, Signal transduction
Positive Control: A431 cells, Breast or Bladder cancer
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: ~170 kDa (wild type) and ~145 kDa (vIII variant)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for EGFR (GFR450), 1mg/mL?

The catalog number for EGFR (GFR450), 1mg/mL is BNUM0450-50.

What sizes are available for EGFR (GFR450), 1mg/mL?

EGFR (GFR450), 1mg/mL is available in the following size(s): 1x 50 µL.

Is EGFR (GFR450), 1mg/mL in stock?

EGFR (GFR450), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR (GFR450), 1mg/mL?

EGFR (GFR450), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFR (GFR450), 1mg/mL?

Estimated delivery time for EGFR (GFR450), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFR (GFR450), 1mg/mL?

The safety data sheet for EGFR (GFR450), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is EGFR (GFR450), 1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.