EGFR (GFR450), CF488A conjugate, 0.1mg/mL — image 1 of 5

Product details

EGFR (GFR450), CF488A conjugate, 0.1mg/mL

Catalog number BNC880450-500

Price for BNC880450-500

Size / count 1x 500 µL

About this product

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, β cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC880450-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EGFR
Gene ID: 1956
NCBI Gene ID: 488293
UniProt: P00533
Swiss Prot: P00533
Host: Mouse
Species Reactivity: Human
Reactivity: EGFR
Immunogen: Recombinant extracellular domain of human EGFR protein
Target Antigen: EGFR
Clonality: Monoclonal
Clone: GFR450
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified)
Field of Research: Cancer, Signal transduction
Positive Control: A431 cells, Breast or Bladder cancer
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~170 kDa (wild type) and ~145 kDa (vIII variant)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for EGFR (GFR450), CF488A conjugate, 0.1mg/mL?

The catalog number for EGFR (GFR450), CF488A conjugate, 0.1mg/mL is BNC880450-500.

What sizes are available for EGFR (GFR450), CF488A conjugate, 0.1mg/mL?

EGFR (GFR450), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is EGFR (GFR450), CF488A conjugate, 0.1mg/mL in stock?

EGFR (GFR450), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR (GFR450), CF488A conjugate, 0.1mg/mL?

EGFR (GFR450), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFR (GFR450), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for EGFR (GFR450), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFR (GFR450), CF488A conjugate, 0.1mg/mL?

The safety data sheet for EGFR (GFR450), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100d33/msds/bnc880450-500.pdf.

What is EGFR (GFR450), CF488A conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.