Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL

Catalog number BNC941231-100

Price for BNC941231-100

Size / count 1x 100 µL

About this product

Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941231-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Eosinophil peroxidase heavy chain; EPER; EPO; EPP; EPX; EPX PEN; PERE
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: EPX
Gene ID: 8288
NCBI Gene ID: 279259
UniProt: P11678
Swiss Prot: P11678
Host: Mouse
Species Reactivity: Human
Reactivity: Eosinophil Peroxidase
Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome
Target Antigen: Eosinophil Peroxidase
Clonality: Monoclonal
Clone: AHE-1
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified)
Field of Research: Immunology
Positive Control: MCF-7 cells. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa (55 kDa-Heavy Chain; 15 kDa-Light Chain)
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Leukocyte Biol (1989) 46:109-118. (RIA) J Exp Med (1991) 173, 117-126. (IHC, FFPE) Clin Exp Immunol (1993) 92:58-64. (ELISA, IP, functional studies, Flow) Gastroenterology (2011) 142(1): 15-20. (IHC, frozen)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL?

The catalog number for Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL is BNC941231-100.

What sizes are available for Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL?

Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL in stock?

Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL?

Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.