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Product details

Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL

Catalog number BNC471231-100

Price for BNC471231-100

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Size / count 1x 100 µL

About this product

Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471231-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Eosinophil peroxidase heavy chain; EPER; EPO; EPP; EPX; EPX PEN; PERE
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EPX
Gene ID
8288
NCBI Gene ID
279259
UniProt
P11678
Swiss Prot
P11678
Host
Mouse
Species Reactivity
Human
Reactivity
Eosinophil Peroxidase
Immunogen
Human eosinophils from a patient with hypereosinophilic syndrome
Target Antigen
Eosinophil Peroxidase
Clonality
Monoclonal
Clone
AHE-1
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified)
Field of Research
Immunology
Positive Control
MCF-7 cells. Tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
70 kDa (55 kDa-Heavy Chain; 15 kDa-Light Chain)
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Leukocyte Biol (1989) 46:109-118. (RIA) J Exp Med (1991) 173, 117-126. (IHC, FFPE) Clin Exp Immunol (1993) 92:58-64. (ELISA, IP, functional studies, Flow) Gastroenterology (2011) 142(1): 15-20. (IHC, frozen)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL?

The catalog number for Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL is BNC471231-100.

What sizes are available for Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL?

Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL in stock?

Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL?

Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029f061270361e10341b/msds/bnc471231-100.pdf.

What is Eosinophil Peroxidase (AHE-1), CF647 conjugate, 0.1mg/mL used for?

Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immun

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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