SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL

Catalog number BNC741578-100

Price for BNC741578-100

Size / count 1x 100 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC741578-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ADD 1; bHLHd1; Class D basic helix-loop-helix protein 1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1c; SREBP-1; Sterol Regulatory Element Binding Transcription Factor 1 / Protein 1; Sterol regulatory element binding transcription factor 1; Sterol regulatory element-binding transcription factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SREBF1
Gene ID: 6720
NCBI Gene ID: 592123
UniProt: P36956
Swiss Prot: P36956
Host: Mouse
Species Reactivity: Human
Reactivity: SREBP1
Immunogen: Recombinant full-length human SREBF1 protein
Target Antigen: SREBP1
Clonality: Monoclonal
Clone: SREBP1/1578
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Ubiqutious expression in adult and fetal tissues.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 68/125 kDa mature/precursor
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL?

The catalog number for SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL is BNC741578-100.

What sizes are available for SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL in stock?

SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL?

SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL?

The safety data sheet for SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b7061270361e10ba3c/msds/bnc741578-100.pdf.

What is SREBP1 (SREBP1/1578), CF740 conjugate, 0.1mg/mL used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.