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Product details

Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL

Catalog number BNC680455-100

Price for BNC680455-100

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Size / count 1x 100 µL

About this product

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER-alpha and ER-beta are differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER-alpha and ER-beta may be regulated by distinct mechanisms even though they share many functional characteristics.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC680455-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen nuclear receptor beta variant a, estrogen nuclear receptor beta variant b, estrogen receptor 2 (ER beta), estrogen receptor beta 4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ESR2
Gene ID
2100
NCBI Gene ID
660607
UniProt
Q92731
Swiss Prot
Q92731
Host
Mouse
Species Reactivity
Horse, Human, Monkey, Mouse, Pig, Rat, Sheep
Reactivity
Estrogen Receptor Beta 1
Immunogen
C-terminus fragment of recombinant human estrogen receptor beta protein
Target Antigen
Estrogen Receptor Beta 1
Clonality
Monoclonal
Clone
ERb455
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Endocrinology, Nuclear receptors
Positive Control
MCF-7 Cells. Ovarian, Breast, Bladder, Gastric or Salivary carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
53-59 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL?

The catalog number for Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL is BNC680455-100.

What sizes are available for Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL?

Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL in stock?

Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL?

Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101a72/msds/bnc680455-100.pdf.

What is Estrogen Receptor beta 1 (ERb455), CF568 conjugate, 0.1mg/mL used for?

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER-alpha and ER-beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of repro

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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