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Product details

Fibronectin (TV-1), 0.2mg/mL

Catalog number BNUB0029-100

Price for BNUB0029-100

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Size / count 1x 100 µL

About this product

Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. The epitope recognized by this antibody is not accessible to the circulating MAb in normal tissues, indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB0029-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cold insoluble globulin (CIG) ; FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF) ; Ugl-Y3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FN1
Gene ID
2335
NCBI Gene ID
203717
UniProt
P02751
Swiss Prot
P02751
Host
Mouse
Species Reactivity
Human, Mouse, Pig, Rat
Reactivity
Fibronectin
Immunogen
T-cell lymphoma biopsy
Target Antigen
Fibronectin
Clonality
Monoclonal
Clone
TV-1
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |IHC, frozen (published) |IHC, FFPE (verified) |WB (published)
Field of Research
Cell adhesion, Extracellular matrix
Positive Control
SW156 cells or Kidney
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
220 kDa (monomer) ; 440 kDa (dimer)
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Cancer Res (1995) 55: 2673-2680. (IHC, frozen; WB; in vivo tumor targeting) BMC Cancer (2006) 6: 8. (Flow, surface)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Fibronectin (TV-1), 0.2mg/mL?

The catalog number for Fibronectin (TV-1), 0.2mg/mL is BNUB0029-100.

What sizes are available for Fibronectin (TV-1), 0.2mg/mL?

Fibronectin (TV-1), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Fibronectin (TV-1), 0.2mg/mL in stock?

Fibronectin (TV-1), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Fibronectin (TV-1), 0.2mg/mL?

Fibronectin (TV-1), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Fibronectin (TV-1), 0.2mg/mL?

Estimated delivery time for Fibronectin (TV-1), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Fibronectin (TV-1), 0.2mg/mL?

The safety data sheet for Fibronectin (TV-1), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1016bb/msds/bnub0029-100.pdf.

What is Fibronectin (TV-1), 0.2mg/mL used for?

Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying bas

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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