Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL

Catalog number BNC040029-500

Price for BNC040029-500

Size / count 1x 500 µL

About this product

Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. The epitope recognized by this antibody is not accessible to the circulating MAb in normal tissues, indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040029-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cold insoluble globulin (CIG) ; FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF) ; Ugl-Y3
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FN1
Gene ID: 2335
NCBI Gene ID: 203717
UniProt: P02751
Swiss Prot: P02751
Host: Mouse
Species Reactivity: Human, Mouse, Pig, Rat
Reactivity: Fibronectin
Immunogen: T-cell lymphoma biopsy
Target Antigen: Fibronectin
Clonality: Monoclonal
Clone: TV-1
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |IHC, frozen (published) |IHC, FFPE (verified) |WB (published)
Field of Research: Cell adhesion, Extracellular matrix
Positive Control: SW156 cells or Kidney
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 220 kDa (monomer) ; 440 kDa (dimer)
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Cancer Res (1995) 55: 2673-2680. (IHC, frozen; WB; in vivo tumor targeting) BMC Cancer (2006) 6: 8. (Flow, surface)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL?

The catalog number for Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL is BNC040029-500.

What sizes are available for Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL?

Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL in stock?

Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL?

Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Fibronectin (TV-1), CF405S conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.