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Product details

Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL

Catalog number BNC940029-100

Price for BNC940029-100

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Size / count 1x 100 µL

About this product

Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. The epitope recognized by this antibody is not accessible to the circulating MAb in normal tissues, indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940029-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cold insoluble globulin (CIG) ; FINC; FN1; FNZ; GFND; GFND2; LETS; Migration stimulating factor (MSF) ; Ugl-Y3
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FN1
Gene ID
2335
NCBI Gene ID
203717
UniProt
P02751
Swiss Prot
P02751
Host
Mouse
Species Reactivity
Human, Mouse, Pig, Rat
Reactivity
Fibronectin
Immunogen
T-cell lymphoma biopsy
Target Antigen
Fibronectin
Clonality
Monoclonal
Clone
TV-1
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |IHC, frozen (published) |IHC, FFPE (verified) |WB (published)
Field of Research
Cell adhesion, Extracellular matrix
Positive Control
SW156 cells or Kidney
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
220 kDa (monomer) ; 440 kDa (dimer)
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Cancer Res (1995) 55: 2673-2680. (IHC, frozen; WB; in vivo tumor targeting) BMC Cancer (2006) 6: 8. (Flow, surface)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL?

The catalog number for Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL is BNC940029-100.

What sizes are available for Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL?

Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL in stock?

Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL?

Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Fibronectin (TV-1), CF594 conjugate, 0.1mg/mL used for?

Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying bas

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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