FOXP3 (3G3), CF594 conjugate, 0.1mg/mL

Catalog number BNC940645-100

Price for BNC940645-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 47-55 kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion (amino acids 2-136) of the protein.The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC940645-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: JM2, AIID, DIETER, IPEX, MGC141961, MGC141963, PIDX, XPID, FOXP3delta7, forkhead box protein P3, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, scurfin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FOXP3
Gene ID: 50943
NCBI Gene ID: 247700
UniProt: Q9BZS1
Swiss Prot: Q9BZS1
Host: Mouse
Species Reactivity: Human, Monkey, Mouse
Reactivity: FOXP3
Immunogen: Full-length His-tagged mouse FOXP3 protein
Target Antigen: FOXP3
Clonality: Monoclonal
Clone: 3G3
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (published)
Field of Research: Cancer, Developmental biology, Endocrinology, Transcription factors
Positive Control: Tonsil, lymph node or Breast carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 47-55 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (2006) 103(17): 6659-6664. (Flow; epitope mapping) Cytometry Part A (2009) 75A: 1040-1050. (Flow; comparison of anti-FOXP3 clones and fixation methods)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for FOXP3 (3G3), CF594 conjugate, 0.1mg/mL?

The catalog number for FOXP3 (3G3), CF594 conjugate, 0.1mg/mL is BNC940645-100.

What sizes are available for FOXP3 (3G3), CF594 conjugate, 0.1mg/mL?

FOXP3 (3G3), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is FOXP3 (3G3), CF594 conjugate, 0.1mg/mL in stock?

FOXP3 (3G3), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FOXP3 (3G3), CF594 conjugate, 0.1mg/mL?

FOXP3 (3G3), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for FOXP3 (3G3), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for FOXP3 (3G3), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FOXP3 (3G3), CF594 conjugate, 0.1mg/mL?

The safety data sheet for FOXP3 (3G3), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is FOXP3 (3G3), CF594 conjugate, 0.1mg/mL used for?

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.