GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL

Catalog number BNUB0767-100

Price for BNUB0767-100

Size / count 1x 100 µL

About this product

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH) . GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB0767-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: GnRH receptor; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; Type I GnRH receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: GNRHR, LHCGR
Gene ID: 2798 (GNRHR) and 3973 (LHCGR)
NCBI Gene ID: 407587 (GNRHR) 468490 (LHCGR)
UniProt: P30968 (GNRHR); P22888 (LHCGR)
Swiss Prot: P30968 (GNRHR) & P22888 (LHCGR)
Host: Mouse
Species Reactivity: Human, Rat
Reactivity: GnRH Receptor
Immunogen: A synthetic peptide aa 1-29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) from the N-terminal of human GnRH receptor.
Target Antigen: GnRH Receptor
Clonality: Monoclonal
Clone: F1G4
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Endocrinology
Positive Control: T47D cells. Pituitary gland, ovarian or breast cancers.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 54-60 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL?

The catalog number for GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL is BNUB0767-100.

What sizes are available for GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL?

GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL in stock?

GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL?

GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL?

Estimated delivery time for GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL?

The safety data sheet for GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is GnRH-Receptor (LHRH Receptor) (F1G4), 0.2mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.