GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0767-500

Price for BNCB0767-500

Size / count 1x 500 µL

About this product

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH) . GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0767-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: GnRH receptor; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; Type I GnRH receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: GNRHR, LHCGR
Gene ID: 2798 (GNRHR) and 3973 (LHCGR)
NCBI Gene ID: 407587 (GNRHR) 468490 (LHCGR)
UniProt: P30968 (GNRHR); P22888 (LHCGR)
Swiss Prot: P30968 (GNRHR) & P22888 (LHCGR)
Host: Mouse
Species Reactivity: Human, Rat
Reactivity: GnRH Receptor
Immunogen: A synthetic peptide aa 1-29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) from the N-terminal of human GnRH receptor.
Target Antigen: GnRH Receptor
Clonality: Monoclonal
Clone: F1G4
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Endocrinology
Positive Control: T47D cells. Pituitary gland, ovarian or breast cancers.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 54-60 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL?

The catalog number for GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL is BNCB0767-500.

What sizes are available for GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL?

GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL in stock?

GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL?

GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL?

The safety data sheet for GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e1001b8/msds/bncb0767-500.pdf.

What is GnRH-Receptor (LHRH Receptor) (F1G4), Biotin conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.