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Product details

GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0768-100

Price for BNCB0768-100

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Size / count 1x 100 µL

About this product

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH) . GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0768-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
GnRH receptor; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; Type I GnRH receptor
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GNRHR, LHCGR
Gene ID
2798 (GNRHR) and 3973 (LHCGR)
NCBI Gene ID
407587 (GNRHR) 468490 (LHCGR)
UniProt
P30968 (GNRHR); P22888 (LHCGR)
Swiss Prot
P30968 (GNRHR) & P22888 (LHCGR)
Host
Mouse
Species Reactivity
Human
Reactivity
GnRH Receptor
Immunogen
Recombinant full-length human GNRHR protein
Target Antigen
GnRH Receptor
Clonality
Monoclonal
Clone
GNRHR/768
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Endocrinology
Positive Control
T47D cells. Pituitary gland, ovarian or breast cancers.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
54-60 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL?

The catalog number for GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL is BNCB0768-100.

What sizes are available for GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL?

GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL in stock?

GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL?

GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL?

The safety data sheet for GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102671/msds/bncb0768-100.pdf.

What is GnRH-Receptor (LHRH Receptor) (GNRHR/768), Biotin conjugate, 0.1mg/mL used for?

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonado

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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