GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL

Catalog number BNC400768-500

Price for BNC400768-500

Size / count 1x 500 µL

About this product

Recognizes an epitope on the extracellular domain of gonadotropin releasing hormone (GnRH) receptor or luteinizing hormone receptor (LHCGR) . Lutropin (also designated luteinizing hormone) plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Gonadotropin (also designated choriogonadotropin) production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor. GnRH receptor contains seven hydrophobic transmembrane domains connected by hydrophilic extracellular and intracellular loops characteristic of G-protein coupled receptors. GnRH stimulates the gonadotrophs of the anterior pituitary to secrete luteinizing hormone (LH) as well as follicle-stimulating hormone (FSH) . GnRH influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of GnRH on breast carcinoma correlates in part to the degree of tumor differentiation. GnRH-positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. GnRH is present in luteal and granulosa cells as well as in ovarian cell membrane preparations.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400768-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: GnRH receptor; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; Type I GnRH receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: GNRHR, LHCGR
Gene ID: 2798 (GNRHR) and 3973 (LHCGR)
NCBI Gene ID: 407587 (GNRHR) 468490 (LHCGR)
UniProt: P30968 (GNRHR); P22888 (LHCGR)
Swiss Prot: P30968 (GNRHR) & P22888 (LHCGR)
Host: Mouse
Species Reactivity: Human
Reactivity: GnRH Receptor
Immunogen: Recombinant full-length human GNRHR protein
Target Antigen: GnRH Receptor
Clonality: Monoclonal
Clone: GNRHR/768
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |IHC, FFPE (verified)
Field of Research: Cancer, Endocrinology
Positive Control: T47D cells. Pituitary gland, ovarian or breast cancers.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 54-60 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL?

The catalog number for GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL is BNC400768-500.

What sizes are available for GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL?

GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL in stock?

GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL?

GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL?

The safety data sheet for GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is GnRH-Receptor (LHRH Receptor) (GNRHR/768), CF640R conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.