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Product details

HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0052-500

Price for BNCB0052-500

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Size / count 1x 500 µL

About this product

This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH) . HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0052-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CG-alpha; CGA; Chorionic Gonadotrophin Alpha; Follicle Stimulating Hormone Alpha; Follitropin Alpha; FSH-alpha; FSHA; GPH Alpha; GPHA1; LHA; LH-alpha; Luteinizing Hormone Alpha; Lutropin Alpha; Thyroid Stimulating Hormone Alpha; Thyrotropin Alpha; TSHA
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CGA, CGB3
Gene ID
1081 & 1082
NCBI Gene ID
172944 & 119689
UniProt
P01215; P01233
Swiss Prot
P01215 & P01233
Host
Mouse
Species Reactivity
Human
Reactivity
HCG intact
Immunogen
Purified hCG protein
Target Antigen
HCG intact
Clonality
Monoclonal
Clone
HCGab/52
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Endocrinology
Positive Control
JAR or TT Cells. Placenta
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~35 kDa (intact hCG)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL?

The catalog number for HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL is BNCB0052-500.

What sizes are available for HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL?

HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL in stock?

HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL?

HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL?

The safety data sheet for HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HCG-intact (HCGab/52), Biotin conjugate, 0.1mg/mL used for?

This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identi

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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