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Product details

Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL

Catalog number BNUB0315-500

Price for BNUB0315-500

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Size / count 1x 500 µL

About this product

This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan's strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2) . Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB0315-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Heparan sulfate proteoglycan of basement membrane; HSPG; Hspg2; LG3 peptide; Perlecan; PLC; SJS1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HSPG2
Gene ID
3339
NCBI Gene ID
562227
UniProt
P98160
Swiss Prot
P98160
Host
Rat
Species Reactivity
Cow, Fish, Human, Monkey, Mouse, Pig
Reactivity
Heparan Sulfate Proteoglycan
Immunogen
Murine EHS laminin preparation
Target Antigen
Heparan Sulfate Proteoglycan
Clonality
Monoclonal
Clone
A7L6
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
Breast carcinomas, squamous cell carcinomas.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
>400 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL?

The catalog number for Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL is BNUB0315-500.

What sizes are available for Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL?

Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL in stock?

Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL?

Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL?

Estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL?

The safety data sheet for Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e1027e1/msds/bnub0315-500.pdf.

What is Heparan Sulphate Proteoglycan (A7L6), 0.2mg/mL used for?

This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan's strat

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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