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Product details

Heparan Sulphate Proteoglycan (A7L6), 1mg/mL

Catalog number BNUM0315-50

Price for BNUM0315-50

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Size / count 1x 50 µL

About this product

This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan's strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2) . Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0315-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Heparan sulfate proteoglycan of basement membrane; HSPG; Hspg2; LG3 peptide; Perlecan; PLC; SJS1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HSPG2
Gene ID
3339
NCBI Gene ID
562227
UniProt
P98160
Swiss Prot
P98160
Host
Rat
Species Reactivity
Cow, Fish, Human, Monkey, Mouse, Pig
Reactivity
Heparan Sulfate Proteoglycan
Immunogen
Murine EHS laminin preparation
Target Antigen
Heparan Sulfate Proteoglycan
Clonality
Monoclonal
Clone
A7L6
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
Breast carcinomas, squamous cell carcinomas.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
>400 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Rattus norvegicus (laboratory rat)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Heparan Sulphate Proteoglycan (A7L6), 1mg/mL?

The catalog number for Heparan Sulphate Proteoglycan (A7L6), 1mg/mL is BNUM0315-50.

What sizes are available for Heparan Sulphate Proteoglycan (A7L6), 1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Heparan Sulphate Proteoglycan (A7L6), 1mg/mL in stock?

Heparan Sulphate Proteoglycan (A7L6), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Heparan Sulphate Proteoglycan (A7L6), 1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), 1mg/mL?

Estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Heparan Sulphate Proteoglycan (A7L6), 1mg/mL?

The safety data sheet for Heparan Sulphate Proteoglycan (A7L6), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e100201/msds/bnum0315-50.pdf.

What is Heparan Sulphate Proteoglycan (A7L6), 1mg/mL used for?

This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan's strat

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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