Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL

Catalog number BNC880315-100

Price for BNC880315-100

Size / count 1x 100 µL

About this product

This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan's strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2) . Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC880315-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Heparan sulfate proteoglycan of basement membrane; HSPG; Hspg2; LG3 peptide; Perlecan; PLC; SJS1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: HSPG2
Gene ID: 3339
NCBI Gene ID: 562227
UniProt: P98160
Swiss Prot: P98160
Host: Rat
Species Reactivity: Cow, Fish, Human, Monkey, Mouse, Pig
Reactivity: Heparan Sulfate Proteoglycan
Immunogen: Murine EHS laminin preparation
Target Antigen: Heparan Sulfate Proteoglycan
Clonality: Monoclonal
Clone: A7L6
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: Breast carcinomas, squamous cell carcinomas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: >400 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL?

The catalog number for Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL is BNC880315-100.

What sizes are available for Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL in stock?

Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Heparan Sulphate Proteoglycan (A7L6), CF488A conjugate, 0.1mg/mL used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.