Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL

Catalog number BNC400315-500

Price for BNC400315-500

Size / count 1x 500 µL

About this product

This MAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan's strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2) . Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400315-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Heparan sulfate proteoglycan of basement membrane; HSPG; Hspg2; LG3 peptide; Perlecan; PLC; SJS1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: HSPG2
Gene ID: 3339
NCBI Gene ID: 562227
UniProt: P98160
Swiss Prot: P98160
Host: Rat
Species Reactivity: Cow, Fish, Human, Monkey, Mouse, Pig
Reactivity: Heparan Sulfate Proteoglycan
Immunogen: Murine EHS laminin preparation
Target Antigen: Heparan Sulfate Proteoglycan
Clonality: Monoclonal
Clone: A7L6
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: Breast carcinomas, squamous cell carcinomas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: >400 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL?

The catalog number for Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL is BNC400315-500.

What sizes are available for Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL in stock?

Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL?

Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Heparan Sulphate Proteoglycan (A7L6), CF640R conjugate, 0.1mg/mL used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.