Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL — image 1 of 2

Product details

Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL

Catalog number BNC880348-100

Price for BNC880348-100

Size / count 1x 100 µL

About this product

In Western blotting, this antibody detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC880348-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Not Known
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: Not Known
NCBI Gene ID: Not Known
UniProt: Not Known
Swiss Prot: Not Known
Host: Mouse
Species Reactivity: Human
Reactivity: Histiocytoma Marker
Immunogen: Membrane preparation from human hepatocytes
Target Antigen: Histiocytoma Marker
Clonality: Monoclonal
Clone: D11
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Immunology
Positive Control: Liver or histiocytoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 125 kDa -135 kDa
References & Citations: Rudinskaya TD, Poltoranina VS, Baranov VN, Petrovichev NN, Voytenkov BO, Tretyakov LO. D11, a novel monoclonal antibody specific for human mature macrophages and peripheral blood monocytes. Immunol Lett. 1992 Jun;33(1):1-7. | Frenkel MA, Tupitsyn NN, Rudinskaia TD, Poltoranina VS, Lebedeva NB, Volkova MA, Kaletin GI. [Use of a new antimacrophage monoclonal antibody D11 in diagnosis of hemoblastosis]. [Article in Russian] Gematol Transfuziol. 1995 Jul-Aug;40(4):13-6. | Tupitsyn NN, et al. Reactivity of anti-macrophage monoclonal antibody D11 in human leukemia and malignant lymphoma. Int J Cancer. 1996;68(2):160-3. | Petrovichev NN, et al. Antimacrophage monoclonal antibody D11 in the diagnosis of tumors of histiocytic origin. Acta Cytol. 1997;41(2):357-63.?2
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL?

The catalog number for Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL is BNC880348-100.

What sizes are available for Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL?

Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL in stock?

Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL?

Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Histiocytoma Marker (D11), CF488A conjugate, 0.1mg/mL used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.