Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL — image 1 of 2

Product details

Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL

Catalog number BNC400348-500

Price for BNC400348-500

Size / count 1x 500 µL

About this product

In Western blotting, this antibody detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400348-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Not Known
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: Not Known
NCBI Gene ID: Not Known
UniProt: Not Known
Swiss Prot: Not Known
Host: Mouse
Species Reactivity: Human
Reactivity: Histiocytoma Marker
Immunogen: Membrane preparation from human hepatocytes
Target Antigen: Histiocytoma Marker
Clonality: Monoclonal
Clone: D11
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Immunology
Positive Control: Liver or histiocytoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 125 kDa -135 kDa
References & Citations: Rudinskaya TD, Poltoranina VS, Baranov VN, Petrovichev NN, Voytenkov BO, Tretyakov LO. D11, a novel monoclonal antibody specific for human mature macrophages and peripheral blood monocytes. Immunol Lett. 1992 Jun;33(1):1-7. | Frenkel MA, Tupitsyn NN, Rudinskaia TD, Poltoranina VS, Lebedeva NB, Volkova MA, Kaletin GI. [Use of a new antimacrophage monoclonal antibody D11 in diagnosis of hemoblastosis]. [Article in Russian] Gematol Transfuziol. 1995 Jul-Aug;40(4):13-6. | Tupitsyn NN, et al. Reactivity of anti-macrophage monoclonal antibody D11 in human leukemia and malignant lymphoma. Int J Cancer. 1996;68(2):160-3. | Petrovichev NN, et al. Antimacrophage monoclonal antibody D11 in the diagnosis of tumors of histiocytic origin. Acta Cytol. 1997;41(2):357-63.?2
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL?

The catalog number for Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL is BNC400348-500.

What sizes are available for Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL?

Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL in stock?

Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL?

Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Histiocytoma Marker (D11), CF640R conjugate, 0.1mg/mL used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.