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Product details
Catalog number BNUB0580-500
Price for BNUB0580-500
Size / count 1x 500 µL
Eukaryotic histones are basic, water-soluble nuclear proteins that form hetero-octameric nucleosome particles. They wrap 146 base pairs of DNA in a left-handed supealpha-helicalturn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Histone H1 (1415-1), 0.2mg/mL is BNUB0580-500.
Histone H1 (1415-1), 0.2mg/mL is available in the following size(s): 1x 500 µL.
Histone H1 (1415-1), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Histone H1 (1415-1), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for Histone H1 (1415-1), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Histone H1 (1415-1), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Eukaryotic histones are basic, water-soluble nuclear proteins that form hetero-octameric nucleosome particles. They wrap 146 base pairs of DNA in a left-handed supealpha-helicalturn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form th
Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.
Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
