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Product details

BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL

Catalog number BNC741472-100

Price for BNC741472-100

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Size / count 1x 100 µL

About this product

BRCA1 is a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. It combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC) . BRCA1 associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC741472-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BRCA1; Breast and ovarian cancer susceptibility protein 1; Early Onset Breast Cancer 1; Protein phosphatase 1 regulatory subunit 53; RING finger protein 53
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BRCA1
Gene ID
672
NCBI Gene ID
194143
UniProt
P38398
Swiss Prot
P38398
Host
Mouse
Species Reactivity
Human
Reactivity
BRCA1
Immunogen
Recombinant human BRCA1 protein fragment (aa445-620) (exact sequence is proprietary)
Target Antigen
BRCA1
Clonality
Monoclonal
Clone
BRCA1/1472
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cancer
Positive Control
A431 or HeLa Cells. Breast, Ovarian or Renal Cell Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
220 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL?

The catalog number for BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL is BNC741472-100.

What sizes are available for BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL?

BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL in stock?

BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL?

BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL?

The safety data sheet for BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e1037fa/msds/bnc741472-100.pdf.

What is BRCA1 (Breast Marker) (BRCA1/1472), CF740 conjugate, 0.1mg/mL used for?

BRCA1 is a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. It combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome survei

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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