IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL — image 1 of 2

Product details

IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL

Catalog number BNC471152-500

Price for BNC471152-500

Size / count 1x 500 µL

About this product

This antibody recognizes a 45 kDa protein, which is identified as isocitrate dehydrogenase (IDH1) . It belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming alpha-ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of alpha-ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Recently, an inactivating mutation of IDH1 has been implicated in glioblastoma. IDH1 appears to function as a tumor suppressor that, when mutationally inactivated, contributes to tumorigenesis in part through induction of the HIF-1 pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471152-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cytosolic NADP-isocitrate dehydrogenase; Epididymis luminal protein 216; Epididymis secretory protein Li 26; HEL-216; HEL-S-26; ICDH; IDCD; IDH1; IDP; IDPC; Isocitrate dehydrogenase 1 (NADP) soluble; NADP dependent isocitrate dehydrogenase peroxisomal; NADP () -specific ICDH; Oxalosuccinate decarboxylase; PICD
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: IDH1
Gene ID: 3417
NCBI Gene ID: 593422
UniProt: O75874
Swiss Prot: O75874
Host: Mouse
Species Reactivity: Human
Reactivity: IDH1
Immunogen: Recombinant fragment (119 Amino acid residues around aa 280-420) of human IDH1 protein
Target Antigen: IDH1
Clonality: Monoclonal
Clone: IDH1/1152
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Metabolism
Positive Control: HepG2, HeLa, HT29 or MCF7 cells. Breast, Colon or Prostate Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 45-47 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL?

The catalog number for IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL is BNC471152-500.

What sizes are available for IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL?

IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL in stock?

IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL?

IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL?

The safety data sheet for IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a2061270361e104996/msds/bnc471152-500.pdf.

What is IDH1 (IDH1/1152), CF647 conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.