Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0761-100

Price for BNCB0761-100

Size / count 1x 100 µL

About this product

This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0761-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: A2m Marker; Ig alpha 1 Chain C Region; Ig alpha 2 Chain C Region; IGHA1; IGHA2; Immunoglobulin Am1; Immunoglobulin Am2; Immunoglobulin Heavy Constant Alpha 1; Immunoglobulin Heavy Constant Alpha 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: IGHA1
Gene ID: 3493 (IGHA1), 3494 (IGHA2)
NCBI Gene ID: 699841
UniProt: P01876 (IGHA1), P01877 (IGHA2)
Swiss Prot: P01876 (IGHA1), P01877 (IGHA2)
Host: Mouse
Species Reactivity: Human
Reactivity: Human IgA
Immunogen: Purified human alpha heavy chain
Target Antigen: Human IgA
Clonality: Monoclonal
Clone: IA761
Type: Anti-Human Immunoglobulin|Primary
Source: Animal
Origin: Animal
Field of Research: Cancer, Immunology, Inflammation
Positive Control: Daudi, 293T, Raji or hPBL cells. Tonsil or Spleen.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 50-75 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL?

The catalog number for Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL is BNCB0761-100.

What sizes are available for Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL?

Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL in stock?

Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL?

Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human IgA Immunoglobulin (IA761), Biotin conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.