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Product details

Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL

Catalog number BNC680761-100

Price for BNC680761-100

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Size / count 1x 100 µL

About this product

This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC680761-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
A2m Marker; Ig alpha 1 Chain C Region; Ig alpha 2 Chain C Region; IGHA1; IGHA2; Immunoglobulin Am1; Immunoglobulin Am2; Immunoglobulin Heavy Constant Alpha 1; Immunoglobulin Heavy Constant Alpha 2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHA1
Gene ID
3493 (IGHA1), 3494 (IGHA2)
NCBI Gene ID
699841
UniProt
P01876 (IGHA1), P01877 (IGHA2)
Swiss Prot
P01876 (IGHA1), P01877 (IGHA2)
Host
Mouse
Species Reactivity
Human
Reactivity
Human IgA
Immunogen
Purified human alpha heavy chain
Target Antigen
Human IgA
Clonality
Monoclonal
Clone
IA761
Type
Anti-Human Immunoglobulin|Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Immunology, Inflammation
Positive Control
Daudi, 293T, Raji or hPBL cells. Tonsil or Spleen.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
50-75 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL?

The catalog number for Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL is BNC680761-100.

What sizes are available for Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL?

Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL in stock?

Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL?

Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104f89/msds/bnc680761-100.pdf.

What is Human IgA Immunoglobulin (IA761), CF568 conjugate, 0.1mg/mL used for?

This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical li

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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