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Product details

Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL

Catalog number BNC940761-100

Price for BNC940761-100

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Size / count 1x 100 µL

About this product

This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940761-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
A2m Marker; Ig alpha 1 Chain C Region; Ig alpha 2 Chain C Region; IGHA1; IGHA2; Immunoglobulin Am1; Immunoglobulin Am2; Immunoglobulin Heavy Constant Alpha 1; Immunoglobulin Heavy Constant Alpha 2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHA1
Gene ID
3493 (IGHA1), 3494 (IGHA2)
NCBI Gene ID
699841
UniProt
P01876 (IGHA1), P01877 (IGHA2)
Swiss Prot
P01876 (IGHA1), P01877 (IGHA2)
Host
Mouse
Species Reactivity
Human
Reactivity
Human IgA
Immunogen
Purified human alpha heavy chain
Target Antigen
Human IgA
Clonality
Monoclonal
Clone
IA761
Type
Anti-Human Immunoglobulin|Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Immunology, Inflammation
Positive Control
Daudi, 293T, Raji or hPBL cells. Tonsil or Spleen.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
50-75 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL?

The catalog number for Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL is BNC940761-100.

What sizes are available for Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL?

Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL in stock?

Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL?

Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human IgA Immunoglobulin (IA761), CF594 conjugate, 0.1mg/mL used for?

This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical li

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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