IgA Secretory Component (SC05), 1mg/mL

About this product

This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNUM0050-50

Size / count

1x 50 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ECM1

Gene ID

1893

NCBI Gene ID

81071

UniProt

Q16610

Swiss Prot

Q16610

Host

Mouse

Species Reactivity

Human, Rat

Reactivity

IgA Secretory Component

Immunogen

Secretory Component protein isolated from human colostrum

Target Antigen

IgA Secretory Component

Clonality

Monoclonal

Clone

SC05

Type

Anti-Human Immunoglobulin|Primary

Source

Animal

Origin

Animal

Applications

Functional studies (published) |IHC, FFPE (verified) |WB (published)

Field of Research

Cancer, Immunology, Inflammation

Positive Control

Stomach, Lung, or breast tumor

Stability

2 years

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

~80 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Infection Immunity (2010)78(11): 4589-4592. (WB) Clin Exp Immunol (2017) 195: 287-301. (functional studies)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse)

Classification

PBS, no BSA, no sodium azide (CAS 26628-22-8)

Conjugate

Purified, BSA-free