Insulin (2D11-H5), 1mg/mL

Catalog number BNUM0030-50

Price for BNUM0030-50

Size / count 1x 50 µL

About this product

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM0030-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: IDDM2, ILPR, IRDN, MODY10, Proinsulin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: INS
Gene ID: 3630
NCBI Gene ID: 272259
UniProt: P01308
Swiss Prot: P01308
Host: Mouse
Species Reactivity: Cow, Human, Mouse, Pig
Reactivity: Insulin
Immunogen: Purified pig insulin, conjugated to KLH
Target Antigen: Insulin
Clonality: Monoclonal
Clone: 2D11-H5
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (published) |IHC, FFPE (verified)
Field of Research: Endocrinology
Positive Control: MIA PaCa-2 cells or Pancreas
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 6 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (2007) 282(46): 33583-33592. (IHC, FFPE) Histochem Cell Biol (2020) 153: 279-285. (IF)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Insulin (2D11-H5), 1mg/mL?

The catalog number for Insulin (2D11-H5), 1mg/mL is BNUM0030-50.

What sizes are available for Insulin (2D11-H5), 1mg/mL?

Insulin (2D11-H5), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Insulin (2D11-H5), 1mg/mL in stock?

Insulin (2D11-H5), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin (2D11-H5), 1mg/mL?

Insulin (2D11-H5), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin (2D11-H5), 1mg/mL?

Estimated delivery time for Insulin (2D11-H5), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin (2D11-H5), 1mg/mL?

The safety data sheet for Insulin (2D11-H5), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Insulin (2D11-H5), 1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.