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Product details

Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0030-500

Price for BNCB0030-500

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Size / count 1x 500 µL

About this product

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0030-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
IDDM2, ILPR, IRDN, MODY10, Proinsulin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
INS
Gene ID
3630
NCBI Gene ID
272259
UniProt
P01308
Swiss Prot
P01308
Host
Mouse
Species Reactivity
Cow, Human, Mouse, Pig
Reactivity
Insulin
Immunogen
Purified pig insulin, conjugated to KLH
Target Antigen
Insulin
Clonality
Monoclonal
Clone
2D11-H5
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (published) |IHC, FFPE (verified)
Field of Research
Endocrinology
Positive Control
MIA PaCa-2 cells or Pancreas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
6 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (2007) 282(46): 33583-33592. (IHC, FFPE) Histochem Cell Biol (2020) 153: 279-285. (IF)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL?

The catalog number for Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL is BNCB0030-500.

What sizes are available for Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL?

Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL in stock?

Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL?

Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Insulin (2D11-H5), Biotin conjugate, 0.1mg/mL used for?

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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