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Product details

Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL

Catalog number BNC040030-500

Price for BNC040030-500

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Size / count 1x 500 µL

About this product

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC040030-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
IDDM2, ILPR, IRDN, MODY10, Proinsulin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
INS
Gene ID
3630
NCBI Gene ID
272259
UniProt
P01308
Swiss Prot
P01308
Host
Mouse
Species Reactivity
Cow, Human, Mouse, Pig
Reactivity
Insulin
Immunogen
Purified pig insulin, conjugated to KLH
Target Antigen
Insulin
Clonality
Monoclonal
Clone
2D11-H5
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (published) |IHC, FFPE (verified)
Field of Research
Endocrinology
Positive Control
MIA PaCa-2 cells or Pancreas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
6 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (2007) 282(46): 33583-33592. (IHC, FFPE) Histochem Cell Biol (2020) 153: 279-285. (IF)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

The catalog number for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is BNC040030-500.

What sizes are available for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL in stock?

Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL used for?

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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