Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL

Catalog number BNC040030-100

Price for BNC040030-100

Size / count 1x 100 µL

About this product

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040030-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: IDDM2, ILPR, IRDN, MODY10, Proinsulin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: INS
Gene ID: 3630
NCBI Gene ID: 272259
UniProt: P01308
Swiss Prot: P01308
Host: Mouse
Species Reactivity: Cow, Human, Mouse, Pig
Reactivity: Insulin
Immunogen: Purified pig insulin, conjugated to KLH
Target Antigen: Insulin
Clonality: Monoclonal
Clone: 2D11-H5
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (published) |IHC, FFPE (verified)
Field of Research: Endocrinology
Positive Control: MIA PaCa-2 cells or Pancreas
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 6 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (2007) 282(46): 33583-33592. (IHC, FFPE) Histochem Cell Biol (2020) 153: 279-285. (IF)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

The catalog number for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is BNC040030-100.

What sizes are available for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL in stock?

Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Insulin (2D11-H5), CF405S conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.