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Product details

Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL

Catalog number BNC940030-100

Price for BNC940030-100

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Size / count 1x 100 µL

About this product

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC940030-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
IDDM2, ILPR, IRDN, MODY10, Proinsulin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
INS
Gene ID
3630
NCBI Gene ID
272259
UniProt
P01308
Swiss Prot
P01308
Host
Mouse
Species Reactivity
Cow, Human, Mouse, Pig
Reactivity
Insulin
Immunogen
Purified pig insulin, conjugated to KLH
Target Antigen
Insulin
Clonality
Monoclonal
Clone
2D11-H5
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (published) |IHC, FFPE (verified)
Field of Research
Endocrinology
Positive Control
MIA PaCa-2 cells or Pancreas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
6 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Biol Chem (2007) 282(46): 33583-33592. (IHC, FFPE) Histochem Cell Biol (2020) 153: 279-285. (IF)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL?

The catalog number for Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL is BNC940030-100.

What sizes are available for Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL?

Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL in stock?

Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL?

Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Insulin (2D11-H5), CF594 conjugate, 0.1mg/mL used for?

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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