Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0827-500

Price for BNCB0827-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 66 kDa-170 kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this MAb reacts with a 120 kDa protein. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal; expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB0827-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: IVL
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: IVL
Gene ID: 3713
NCBI Gene ID: 516439
UniProt: P07476
Swiss Prot: P07476
Host: Mouse
Species Reactivity: Human
Reactivity: Involucrin
Immunogen: Purified involucrin from human keratinocytes
Target Antigen: Involucrin
Clonality: Monoclonal
Clone: IVRN/827
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: MCF-7 cells. Localized to upper spinous and granular layers in normal skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 66-170 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL?

The catalog number for Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL is BNCB0827-500.

What sizes are available for Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL?

Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL in stock?

Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL?

Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Involucrin (IVRN/827), Biotin conjugate, 0.1mg/mL used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.