Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL

Catalog number BNC400827-100

Price for BNC400827-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 66 kDa-170 kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this MAb reacts with a 120 kDa protein. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal; expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400827-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: IVL
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: IVL
Gene ID: 3713
NCBI Gene ID: 516439
UniProt: P07476
Swiss Prot: P07476
Host: Mouse
Species Reactivity: Human
Reactivity: Involucrin
Immunogen: Purified involucrin from human keratinocytes
Target Antigen: Involucrin
Clonality: Monoclonal
Clone: IVRN/827
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: MCF-7 cells. Localized to upper spinous and granular layers in normal skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 66-170 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL?

The catalog number for Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL is BNC400827-100.

What sizes are available for Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL?

Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL in stock?

Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL?

Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Involucrin (IVRN/827), CF640R conjugate, 0.1mg/mL used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.