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Product details

Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL

Catalog number BNC400681-500

Price for BNC400681-500

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Size / count 1x 500 µL

About this product

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC400681-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGKC
Gene ID
3514
NCBI Gene ID
449609
UniProt
P01601; P01834
Swiss Prot
P01601 & P01834
Host
Mouse
Species Reactivity
Human
Reactivity
Human Kappa Light Chain
Immunogen
Purified human Ig kappa chain
Target Antigen
Human Kappa Light Chain
Clonality
Monoclonal
Clone
HP6053
Type
Anti-Human Immunoglobulin|Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~22.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL?

The catalog number for Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL is BNC400681-500.

What sizes are available for Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL?

Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL in stock?

Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL?

Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human Kappa Light Chain (HP6053), CF640R conjugate, 0.1mg/mL used for?

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 7

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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