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Product details

Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL

Catalog number BNC880709-500

Price for BNC880709-500

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Size / count 1x 500 µL

About this product

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC880709-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGKC
Gene ID
3514
NCBI Gene ID
449609
UniProt
P01601; P01834
Swiss Prot
P01601 & P01834
Host
Mouse
Species Reactivity
Human
Reactivity
Human Kappa Light Chain
Immunogen
Recombinant human Ig kappa chain
Target Antigen
Human Kappa Light Chain
Clonality
Monoclonal
Clone
KLC709
Type
Anti-Human Immunoglobulin|Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~22.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL?

The catalog number for Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL is BNC880709-500.

What sizes are available for Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL?

Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL in stock?

Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL?

Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human Kappa Light Chain (KLC709), CF488A conjugate, 0.1mg/mL used for?

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two li

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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