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Product details

Human Kappa Light Chain (L1C1), 1mg/mL

Catalog number BNUM0018-50

Price for BNUM0018-50

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Size / count 1x 50 µL

About this product

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0018-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGKC
Gene ID
3514
NCBI Gene ID
449609
UniProt
P01601; P01834
Swiss Prot
P01601 & P01834
Host
Mouse
Species Reactivity
Human
Reactivity
Human Kappa Light Chain
Immunogen
Human B-Lymphoma Cells
Target Antigen
Human Kappa Light Chain
Clonality
Monoclonal
Clone
L1C1
Type
Anti-Human Immunoglobulin|Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
~22.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Human Kappa Light Chain (L1C1), 1mg/mL?

The catalog number for Human Kappa Light Chain (L1C1), 1mg/mL is BNUM0018-50.

What sizes are available for Human Kappa Light Chain (L1C1), 1mg/mL?

Human Kappa Light Chain (L1C1), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Human Kappa Light Chain (L1C1), 1mg/mL in stock?

Human Kappa Light Chain (L1C1), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human Kappa Light Chain (L1C1), 1mg/mL?

Human Kappa Light Chain (L1C1), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human Kappa Light Chain (L1C1), 1mg/mL?

Estimated delivery time for Human Kappa Light Chain (L1C1), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human Kappa Light Chain (L1C1), 1mg/mL?

The safety data sheet for Human Kappa Light Chain (L1C1), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human Kappa Light Chain (L1C1), 1mg/mL used for?

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 7

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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