Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL — image 1 of 4

Product details

Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL

Catalog number BNC880729-100

Price for BNC880729-100

Size / count 1x 100 µL

About this product

Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC880729-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Ku (p70) : 70kDa subunit of Ku antigen; ATP dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70kDa subunit; CTC box-binding factor 75kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; G22P1; Ku autoantigen, 70kDa; Ku70; Kup70; Lupus Ku autoantigen protein p70; ML8; Thyroid autoantigen 70kD (Ku antigen) ; Thyroid-lupus autoantigen (TLAA) ; X-ray repair cross-complementing protein 6 (XRCC6) Ku (p80) : 86kDa subunit of Ku antigen; ATP dependent DNA helicase 2 subunit 2; ATP dependent DNA helicase II 86Kd subunit; ATP-dependent DNA helicase II 80kDa subunit; CTC box-binding factor 85kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; KARP1; Ku autoantigen 80kDa; Ku80; Ku86 autoantigen related protein 1; KUB2; Lupus Ku autoantigen protein p86; Nuclear factor IV (NFIV) ; Thyroid-lupus autoantigen (TLAA) ; X-ray repair cross-complementing protein 5 (XRCC5)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: XRCC6
Gene ID: 2547 (p70); 7520 (p80)
NCBI Gene ID: 292493 (p70); 388739 (p80)
UniProt: P12956 (p70); P13010 (p80)
Swiss Prot: P12956 (p70) ; P13010 (p80)
Host: Mouse
Species Reactivity: Human, Non-human primates
Reactivity: Ku-Holo
Immunogen: Nuclear extract of human HL-60 cells
Target Antigen: Ku-Holo
Clonality: Monoclonal
Clone: KU729
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified)
Field of Research: Apoptosis, Cell cycle, Signal transduction
Positive Control: Human cancer K562, HL-60, HEp-2 or HeLa cells
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa & 80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL?

The catalog number for Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL is BNC880729-100.

What sizes are available for Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL?

Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL in stock?

Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL?

Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ku-Holo (p70;83) (KU729), CF488A conjugate, 0.1mg/mL used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.