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Product details

Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL

Catalog number BNUM1214-50

Price for BNUM1214-50

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Size / count 1x 50 µL

About this product

Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG) . The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM1214-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Chorionic Gonadotropin, Beta polypeptide 4 (CGB4) ; hLHB; Interstitial cell stimulating hormone beta chain; Leutropin; LH-B; LHB; LSH-B; LSH-beta; Luteinizing hormone beta polypeptide; Lutropin beta chain
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
LHB
Gene ID
3972
NCBI Gene ID
154704
UniProt
P01229
Swiss Prot
P01229
Host
Mouse
Species Reactivity
Human
Reactivity
Luteinizing Hormone-Beta
Immunogen
Recombinant beta sub-unit of human LH
Target Antigen
Luteinizing Hormone-Beta
Clonality
Monoclonal
Clone
LHb/1214
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Endocrinology
Positive Control
Anterior Pituitary
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
22 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL?

The catalog number for Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL is BNUM1214-50.

What sizes are available for Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL?

Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL in stock?

Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL?

Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL?

Estimated delivery time for Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL?

The safety data sheet for Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Luteinizing Hormone beta (LH beta) (LHb/1214), 1mg/mL used for?

Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotrop

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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