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Product details

Macrophage Specific Antigen (LN-5), 0.2mg/mL

Catalog number BNUB0059-500

Price for BNUB0059-500

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Size / count 1x 500 µL

About this product

This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffers cells of the liver and Langerhans cells of the skin. Macrophages comprise of many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone marrow. After passing through the monoblast and pro-monocyte states of the monocyte stage, they enter the blood, where they circulate for about 40 hours. They then enter tissues and increase in size, phagocytic activity, and lysosomal enzyme content becoming macrophages. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, specific phagocytosis of opsonized microorganisms mediated by Fc receptors and complement receptors, killing of ingested microorganisms, digestion and presentation of antigens to T and B lymphocytes, and secretion of a large number of diverse products, including many enzymes including lysozyme and collagenases, several complement components and coagulation factors, some prostaglandins and leukotrienes, and many regulatory molecules (Interferon, Interleukin 1) . LN-5 selectively stains human sebaceous glands in formalin-fixed, paraffin-embedded skin samples. Undifferentiated sebocyte progenitors are negative, and only sebocytes from the onset of their differentiation reveal positive cytoplasmic staining.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Specifications

Catalog number
BNUB0059-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Not Known
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
Not Known
NCBI Gene ID
Not Known
UniProt
Not Known
Swiss Prot
Not Known
Host
Mouse
Species Reactivity
Human
Reactivity
Macrophage Specific Antigen
Immunogen
Human peripheral blood mononuclear cells
Target Antigen
Macrophage Specific Antigen
Clonality
Monoclonal
Clone
LN-5
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Immunology
Positive Control
Liver or histiocytoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
Not Known
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Blood (1988) 71(4): 1079-1085. (IHC, FFPE)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgM, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Macrophage Specific Antigen (LN-5), 0.2mg/mL?

The catalog number for Macrophage Specific Antigen (LN-5), 0.2mg/mL is BNUB0059-500.

What sizes are available for Macrophage Specific Antigen (LN-5), 0.2mg/mL?

Macrophage Specific Antigen (LN-5), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Macrophage Specific Antigen (LN-5), 0.2mg/mL in stock?

Macrophage Specific Antigen (LN-5), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Macrophage Specific Antigen (LN-5), 0.2mg/mL?

Macrophage Specific Antigen (LN-5), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Macrophage Specific Antigen (LN-5), 0.2mg/mL?

Estimated delivery time for Macrophage Specific Antigen (LN-5), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Macrophage Specific Antigen (LN-5), 0.2mg/mL?

The safety data sheet for Macrophage Specific Antigen (LN-5), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e1022ab/msds/bnub0059-500.pdf.

What is Macrophage Specific Antigen (LN-5), 0.2mg/mL used for?

This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffers cells of the liver and Langerhans cells of the skin. Macrophages comprise of many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone ma

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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