MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL

Catalog number BNC940008-500

Price for BNC940008-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 42-46 kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8 T lymphocyte clones (CTL) . The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs) . Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC940008-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, MAGEA1, Melanoma antigen family A 1, Melanoma associated antigen 1, Melanoma associated antigen MZ2 E
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MAGEA1
Gene ID: 4100
NCBI Gene ID: 72879
UniProt: P43355
Swiss Prot: P43355
Host: Mouse
Species Reactivity: Dog, Human, Rat
Reactivity: MAGE-A1
Immunogen: Human MAGE-A1 full length recombinant protein
Target Antigen: MAGE-A1
Clonality: Monoclonal
Clone: MA454
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (published) |ELISA (published) |IHC, FFPE (verified) |WB (published)
Field of Research: Cancer
Positive Control: Melanoma cell lines. Melanomas or testicular carcinomas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 42-46 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1994) 91: 1004-1008. (WB; ELISA) Br J Cancer (2000) 83(4): 493-497. (IHC, FFPE) Int J Cancer (2001) 94: 252-256. (IHC, FFPE) Cancer Immunol Immunother (2013) 62: 605-614. (Flow, intracellular)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL?

The catalog number for MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL is BNC940008-500.

What sizes are available for MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL?

MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL in stock?

MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL?

MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MAGE A1 (MA454), CF594 conjugate, 0.1mg/mL used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.