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Product details
Catalog number BNUB0224-100
Price for BNUB0224-100
Size / count 1x 100 µL
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Major Vault Protein (MVP) (1014), 0.2mg/mL is BNUB0224-100.
Major Vault Protein (MVP) (1014), 0.2mg/mL is available in the following size(s): 1x 100 µL.
Major Vault Protein (MVP) (1014), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Major Vault Protein (MVP) (1014), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for Major Vault Protein (MVP) (1014), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Major Vault Protein (MVP) (1014), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100d64/msds/bnub0224-100.pdf.
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70%
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.
