Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL

Catalog number BNC880224-500

Price for BNC880224-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC880224-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Lung resistance-related protein (LRP) ; Major Vault Protein; MVP; VAULT1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MVP
Gene ID: 9961
NCBI Gene ID: 632177
UniProt: Q14764
Swiss Prot: Q14764
Host: Mouse
Species Reactivity: Human
Reactivity: Major Vault Protein
Immunogen: Proteins precipitated from human breast cancer MCF-7 cells
Target Antigen: Major Vault Protein
Clonality: Monoclonal
Clone: 1014
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |WB (verified)
Field of Research: Cancer, Endocrinology
Positive Control: MCF-7/HeLa, breast tumors
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 104-110 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL?

The catalog number for Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL is BNC880224-500.

What sizes are available for Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL in stock?

Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Major Vault Protein (MVP) (1014), CF488A conjugate, 0.1mg/mL used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.