Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL

Catalog number BNC470224-500

Price for BNC470224-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470224-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Lung resistance-related protein (LRP) ; Major Vault Protein; MVP; VAULT1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MVP
Gene ID: 9961
NCBI Gene ID: 632177
UniProt: Q14764
Swiss Prot: Q14764
Host: Mouse
Species Reactivity: Human
Reactivity: Major Vault Protein
Immunogen: Proteins precipitated from human breast cancer MCF-7 cells
Target Antigen: Major Vault Protein
Clonality: Monoclonal
Clone: 1014
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |WB (verified)
Field of Research: Cancer, Endocrinology
Positive Control: MCF-7/HeLa, breast tumors
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 104-110 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL?

The catalog number for Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL is BNC470224-500.

What sizes are available for Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL in stock?

Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b3061270361e10a65a/msds/bnc470224-500.pdf.

What is Major Vault Protein (MVP) (1014), CF647 conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.