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Product details
Catalog number BNUM0225-50
Price for BNUM0225-50
Size / count 1x 50 µL
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Major Vault Protein (MVP) (1032), 1mg/mL is BNUM0225-50.
Major Vault Protein (MVP) (1032), 1mg/mL is available in the following size(s): 1x 50 µL.
Major Vault Protein (MVP) (1032), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Major Vault Protein (MVP) (1032), 1mg/mL is manufactured by Biotium.
Estimated delivery time for Major Vault Protein (MVP) (1032), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Major Vault Protein (MVP) (1032), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70%
Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.
Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
