Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL — image 1 of 2

Product details

Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL

Catalog number BNC040225-500

Price for BNC040225-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040225-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Lung resistance-related protein (LRP) ; Major Vault Protein; MVP; VAULT1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MVP
Gene ID: 9961
NCBI Gene ID: 632177
UniProt: Q14764
Swiss Prot: Q14764
Host: Mouse
Species Reactivity: Human
Reactivity: Major Vault Protein
Immunogen: Proteins precipitated from human breast cancer MCF-7 cells
Target Antigen: Major Vault Protein
Clonality: Monoclonal
Clone: 1032
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (published)
Field of Research: Cancer, Endocrinology
Positive Control: MCF-7/HeLa, breast tumors
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 104-110 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Mol Cell Proteomics (2013) 12(7): 2006-2020. (WB)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL?

The catalog number for Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL is BNC040225-500.

What sizes are available for Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL in stock?

Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.